Banca de QUALIFICAÇÃO: GIOVANA THAÍS SOARES PEREIRA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE: GIOVANA THAÍS SOARES PEREIRA
DATA: 16/04/2026
HORA: 14:00
LOCAL: Hibrido
TÍTULO:

Mycotoxin Deactivator Improves Performance and Antioxidant Status, and Reduces Oxidative Stress in Gestating and Lactating Gilts Fed Diets Containing Purified Mycotoxins

PALAVRAS-CHAVES:

Deactivator; gestation; lactation; mycotoxins; oxidative stress; sows

PÁGINAS: 30
GRANDE ÁREA: Ciências Agrárias
ÁREA: Zootecnia
SUBÁREA: Nutrição e Alimentação Animal
ESPECIALIDADE: Avaliação de Alimentos para Animais
RESUMO:

Mycotoxins such as deoxynivalenol (DON), zearalenone (ZEA) and fumonisin (FUM), produced by Fusarium fungi, commonly contaminate cereals used in swine diets and can impair cellular function, generating oxidative stress and metabolic dysfunctions. Prepubertal and reproductive females are particularly sensitive to these compounds. The present study aimed to evaluate the impact of the supplementation of a mycotoxin deactivator composed by adsorbent clay minerals, inactivated fermentation extracts of Saccharomyces cerevisiae, blend of antioxidants, organic acids and botanicals in diets containing purified mycotoxins on the productive and reproductive performance of gestating and lactating sows and their litters, as well as on serum oxidative and redox metabolites. Sixty commercial gilts were assigned to three treatments: a standard control diet as negative control (NC; mycotoxin levels at accepted regulatory Brazilian Ministry of Agriculture standards Deoxynivalenol (DON): <100 ug kg-1; Zearalenone (ZEA): <20 ug kg-1 Fumonisins (FB): <1 mg kg-1), a standard diet added with purified mycotoxins to reach a contamination level considered as positive (NCP-; DON at 2.5 mg kg−1, FB at 10 mg kg−1, and ZEA at 0.75 mg kg−1) without deactivator; and a positive added the deactivator at an inclusion rate of 2 kg ton-1 (NCP+). Experimental diets were provided from d 75 to 115 of gestation and from d 1 to 23 of lactation. Feed intake and body weight were monitored, and blood samples were collected at different stages. Antioxidant enzymes (glutathione peroxidase (GPx) and total superoxide dismutase (TSOD)), vitamins (Vit A, E, and C), and malondialdehyde (MDA)) were evaluated in erythrocyte and plasma samples. Sows exposed to mycotoxins showed increased mortality and reduced antioxidant status (↓GPx, ↓TSOD, ↓Vit A, ↓Vit E and ↓Vit C) and a higher oxidative damage to lipids (↑MDA) when compared to the control and deactivator associated treatment. Supplementation with the adsorbent improved serum antioxidant enzymes and vitamin levels in sows and their litters, suggesting enhanced cellular protection and a better overall antioxidant response. Our findings showed that the use of a mycotoxin deactivator can mitigate the negative impacts on performance and oxidative stress when sows and their litters are subjected to diet contaminated by mycotoxins.

MEMBROS DA BANCA:
Externo à Instituição - WAGNER AZIS GARCIA DE ARAÚJO - IFMG (Membro)
Presidente - MARVIO LOBAO TEIXEIRA DE ABREU (Membro)
Interno - LUCIANA DE PAULA NAVES (Suplente)
Externo à Instituição - CRISTINA MARIA LIMA SÁ FORTES - UFMG (Membro)